Specialists of BIOTA LLC are testing a system of biological plant protection products and fertilizers for winter wheat (corn was planted in the previous year on the field). In the autumn of 2021 and spring 2022 BIOTA’s biological products have been used to treat crop residues (remaining from corn) and winter wheat seedlings in the Krasnodar region. These treatments demonstrate a significant advantage of the biological method of plant protection over the traditional chemical technology. After treatment with biological agents, the growth of seedlings is approximately 30% higher than that of those treated with chemical agents.